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It is also possible that GLP-1 drugs can penetrate the blood-brain barrier and might aid in the clearance of beta-amyloid, the toxic protein that is a hallmark of Alzheimers disease

June 2009

The production of PGE 2 during efferocytosis leads to the suppression of the phagocytosis and killing function of alveolar macrophages, in vitro, via EP2adenylyl cyclasecAMP pathway

My Day This is the section I refer to as the home page

Why Weekly Dosing Beats Irregular Schedules for Maintenance Maintenance dosingcontinuing weekly injections after reaching your target weightkeeps GLP-1 activity constant and prevents metabolic adaptation

From there I share the dosing protocol I've been using on myself, including a four-on, three-off cycle to keep tolerance low, plus what I've noticed in terms of mood, mental energy, and the lack of any real come-down or withdrawal